Studies have revealed a link between long work hours and risk of cardiovascular disease. A new study shows it’s a dose-response situation: the more hours you work, the bigger the risk. The research found that for every extra hour of work put in weekly (over a decade), your risk goes up 1 percent. If you work 55 hours a week, your risk jumps 16 percent - work 65 hours, your risk rises 52 percent. If you clock 75 hours a week working, you double your likelihood for cardiovascular disease (stroke, heart attack, etc.).